Affiliation:
1. Sichuan University of Science & Engineering
2. Sichuan University of Science and Engineering
Abstract
Gamma cyclodextrin was produced synthesized from beta cyclodextrin in the presence of glycyrrhizin, using Cyclodextrin glucanotransferase (EC 2.4.1.19) from AlkalophilicBacillus. The results showed that more than 32.7% of beta cyclodextrin substrate was converted to the corresponding gamma cyclodextrin under the following conditions, viz. 200 units enzyme/g of β-CD, 10mmol/L of β-CD concentration, 3% of glycyrrhizin concentration, 27 h of reaction time, 65°C of temperature and a reaction pH of 7.0.
Publisher
Trans Tech Publications, Ltd.
Reference7 articles.
1. J.K. Lee, H.S. Kim: Enzyme Microb. Technol. Vol. 13(1991), p.499.
2. J. Szejtli: Cyclodextrin Technology (Kluwer, Dordrecht, The Netherlands 1988), p.79.
3. O. Bekers, E.V. Uijitendaal, J. H. Beijnen, A. bult, and W.J.M. Underberg: Drug Dev. Ind. Pharm. Vol. 17(1991), p.1503.
4. J.H. Lee, K.H. Choi, Y.S. Lee, I.B. Know, J.H. Yu: Enzyme Microb. Technol. Vol. 14(1992), p.1017.
5. M. Sato, Y. Yagi: Washington, DC: American Chemical Society. (1991), p.125.