Continuous Flow Synthesis of Coumarin
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Published:2013-09
Issue:
Volume:781-784
Page:936-941
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ISSN:1662-8985
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Container-title:Advanced Materials Research
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language:
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Short-container-title:AMR
Author:
Chen An Bang1, Li Xin1, Zhou Yang Zhi1, Huang Ling Ling1, Fang Zheng1, Gan Hai Feng1, Guo Kai1
Affiliation:
1. Nanjing University of Technology
Abstract
Flow chemistry, as a rapidly emerging technology, is exploited to provide a safe and scalable route for the pharmaceutically interesting coumarin. Here, a continuous flow approach for the generation of coumarin is reported, which relies on the two connected coil reactors design. The synthesis of coumarin has been performed successfully in high conversion on small scale and can be scaled up substantially.
Publisher
Trans Tech Publications, Ltd.
Subject
General Engineering
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