Optimization for Purification Technology of Platycodins by Macroreticular Resin

Abstract

In order to purify the platycodins from Platycodon grandiflorum, AB-8 macroporous resin was used to test. Based on single factor experiments, orthogonal test was used to optimum the purification conditions. Adsorption pH, adsorption temperature, adsorption time and platycodins concentration were as factors and adsorption capacity was as index. The results were as follows: adsorption pH 6.0, adsorption temperature 40°C, adsorption tim110min, platycodins concentration 2.0mg/mL were the optimization conditions.The adsorption quantity reached at 39.1mg/g. So AB-8 macroporous resin was a suitable resin for purify the platycodins from Platycodon grandiflorum.