Impact of Nanopowders on Exraction Yield of Centella asiatica

Abstract

Centella asiatica (C. Asiatica) is a traditional herb that has been used in raditional medicine especially in Asia region. Recently the pharmalogical study of Asiatic acid (AA) which is one of bioactive constituents in C. Asiatica has been studied and revealed that this compound has a potential to be use in medicine area. The objective of this paper is to produce nanoparticles C. Asiatica by Planetary Ball Mill (PBM) and determined the effect of nanonization on extraction yield of asiatic acid. The particles were analyzed using particle sizer to determine size of particle produce and the morphology was evaluated through FESEM. As a result, the mean particles size of nanopowders was 501.10 nm and the extraction of asiatic acid using nanopowders showed 82.09 % higher than original powder.