The Balance between Bone Formation and Material Resorption in Unidirectional Porous β-Tricalcium Phosphate Implanted in a Rabbit Tibia

Abstract

We examined the balance between bone formation and material resorption in β-tricalcium phosphate, with unidirectional pores (porosity of 57%) and micropore structure. Using an animal bone defect model, rapid bone formation reached to the center of the material, while the material remained at the same period. Histomorphometric analysis showed that the sum total area of formed bone and material gradually increased with time throughout the experiment. These results indicate that the balance between bone formation and material resorption in this material is satisfactory.