Solvatochromism and Electroabsorption Studies of Drug Carriers

Abstract

2, 6-Diaminoanthraquinone is used in drug delivery. The absorption and fluorescence spectral properties of 2,6-Diaminoanthraquinone (DAAQ) have been investigated in a series of organic solvents with different polarity functions ranging from 0.207 to 0.762.The different solvents used are Tetrahydrofuran (THF) (0.207), Dimethylformamide (DMF) (0.404), ethanol (0.654) and Methonal (0.762).The fluorescence shifts are more pronounced than the absorption shifts indicating that the change in dipole moment is positive. The change in dipole moment and the ratio of the dipole moments are determined and discussed by Solvatochromism method. The third order nonlinearity of 2,6-DAAQ in PVA dissolved in DMF solution is determined using Electroabsorption. Higher order nonlinearities can be deduced on successful recording of the stark spectrum at the higher order of the applied electric field.