Multiscale Heterogeneity of Bone Microporosities and Tissue Scaffolds

Author:

Kochová Petra1,Gregor Tomáš2,Prosecká Eva3,Eberlová Lada4,Tonar Zbyněk4ORCID

Affiliation:

1. University of West Bohemia

2. University of West Bohemia in Pilsen

3. The Academy of Sciences of the Czech Republic

4. Faculty of Medicine in Pilsen, Charles University in Prague

Abstract

Our aim was to use stereology to quantify the volume fraction of osteocyte lacunes, volume fraction of large blood vessels, numerical density of osteocyte lacunes, volume of osteocyte lacunae and bone surface in series of micro-CT images representing samples of spongy and compact bone of human tibia. The spongy bone had a smaller volume fraction of osteocyte lacunes, a greater numerical density of bone lacunes, a smaller volume of the lacunes within the same bone volume and a greater bone surface density when compared to the compact bone. Stereology provided us with data on hierarchical organization of bone structural heterogeneity with reasonable time costs.

Publisher

Trans Tech Publications, Ltd.

Subject

Mechanical Engineering,Mechanics of Materials,General Materials Science

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