Hydroxyapatite Nanocomposites for Biological Application

Abstract

Hydroxyapatite is a bioceramic which has a wide range of medical application for bone diseases. To enhance its usage, we have prepared ciprofloxacin loaded nanohydroxyapatite (HA) composite with a natural polymer, alginate, using wet chemical method at low temperature. The prepared composites were analyzed by various physicochemical methods. The results show that the nanoHA crystallites are well intact with the alginate macromolecules. For the composite system FT-IR study is done. The drug is pre-adsorbed onto the ceramic particle before the formation of composite. The thermal behavior of composite has been studied using thermo gravimetric analysis (TGA). This paper communicated the Influence of Polymer concentration on the Controlled drug release from hydroxyapatite Nanocomposites