Effect of Ag, Cu, and ZnO Nanoparticle Suspensions on the Antimicrobial Activity of Tribulus Terrestris Herbal Extracts

Abstract

In this study, the antimicrobial growth inhibition and mechanistic activities of silver (Ag NPs), zinc oxide (ZnO NPs), and copper (Cu NPs) nanoparticles were investigated in presence of medicinal plant extracts of TribulusTerrestris. The extract in different concentrations (5, 10, 20, and 30%) along with nanoparticles suspension mixture was used for antimicrobial activity testing against some human pathogenic microorganisms. Among the bacterial strains tested, Escherichia coli and Proteus sp were most susceptibile at 30% concentration followed by moderate activity against Morganellasp, EntrococcusFaecalis, Staphylococcus aureus, and Candida albicans.TribulusTerrestris had no effect on Acetobacterspand Streptococcus agalactia. The nanoparticles used in the present investigation have shown excellent antimicrobial activity in the presence of TribulusTerrestris, hence they can be used as potent sources for antibacterial agents.