Synergistic Effect of Tea-Phytochemicals, Noble Metals and Zno Nano-Photo-Composites for Combating Resistance of Bacterial Growth

Abstract

The spontaneous progress in scientific bases to combat infections resulting from pathogenic microbial colonies has led to the development of nanomaterials capped with plant phytochemicals that possess exceptional bacterial growth resistance. In this study, the Authors report an economical biogenic synthesis of zinc oxide nanoparticles and its nanocomposites with silver, gold, and silver-gold bimetal to evaluate their antibacterial potency towards bacterial colonies. Further, these nanomaterials were functionalized with tea-phytochemicals for cost-effective synthesis, as a biogenic capping and reducing agent, for modulating the growth kinetics of nanomaterials, and because of their synergy with the nanomaterials in improving their antibacterial property. The identification of the biosynthesized nanomaterials was performed through various microscopic and spectroscopic techniques. The model microbes chosen to undergo this study were Escherichia coli, a gram-negative bacterium, and Staphylococcus aureus, a gram-positive bacterium. Based on the anti-bacterial essay, certain factors, such as the nature of the bacteria and nanomaterials, the production rates of superoxide radicals, etc. determined the extent of microbial growth inhibition.