Synthesis of <i>L</i>-Azetidine-2-Carboxylic Acid-Reference-Cited by-同舟云学术

Synthesis of L-Azetidine-2-Carboxylic Acid

Published:2012-01 Issue: Volume:455-456 Page:635-638
ISSN:1662-8985
Container-title:Advanced Materials Research
language:
Short-container-title:AMR

Author:

Jin Jian Zhong¹,Zhang Jie²

Affiliation:

1. Zhejiang Shuren University

2. Chinese Academy of Sciences

Abstract

L-Azetidine-2-carboxylic acid, the first known example naturally occurring azetidine, was synthesized in a novel, simple, clean and improved procedure. It was synthesized from γ-butyrolactone through four steps: bromination and esterification, cyclization, hydrogenation and resolution. The overall yield could reach 13.2%.

Publisher

Trans Tech Publications, Ltd.

Subject

General Engineering

Link

https://www.scientific.net/AMR.455-456.635.pdf

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