The Comparison of Polyethersulfone (PES)/N-Methyl 2-Pyrrolidone (NMP) on the Fabrication of Hollow Fiber Membranes with Commercial Membranes for Applications Hemodialysis

Abstract

The decrease in kidney function is caused by an increase in creatinine and urea levels in the blood; this is the cause of chronic kidney failure (GGK) in patients. Hemodialysis membrane technology is an alternative treatment for chronic renal failure by separating dissolved components in the blood, such as creatinine and urea, using dialysate fluid by passing through the membrane pores. Therefore, the characteristics of hemodialysis membranes become essential to meet the requirements of a dialyzer. This study aimed to compare the features of the resulting hemodialysis membrane with several commercial membranes. In this study, there were four kinds of commercial membranes used, namely F8HPS, FX80, LO PS 15, and Nipro Elisio 15-H, were compared with membrane products that have variations in the composition of polyethylene (PES) using N-methyl-2-pyrolidone (NMP) solvents are 22.5; 24; and 25%. The membrane manufacturing method uses nonsolvent-induced precipitation (NISP). The resulting hollow fiber membrane is characterized by surface morphology using a scanning electron microscope (SEM), functional groups (FT-IR), and tensile test analysis (DMA). The results showed that the composition of PES/NMP is 25%, close to the characteristics of Nipro Elisio 15-H.