Extraction of ideogram features for diagnosing chromosomal abnormalities

Abstract

This paper proposes an approach to the detection and extraction of specific features in an ideogram image. Ideogram is a depiction of a healthy chromosome used in a karyotyping process - a procedure designed to diagnose chromosomal abnormalities. Extraction of ideogram features is a part of a general algorithm for the detection of chromosomal abnormlities. According to the general algorithm, both chromosomes and ideograms have to be parsed and converted into a single data format for further comparison. The image of the ideogram is the input data for the algorithm of the extraction of ideogram features, which is proposed in this paper. The output is a data structure containing ideogram properties. A software prototype has been developed to verify the algorithm efficiency.