The Possible Role of Stem Cells in Acupuncture Treatment for Neurodegenerative Diseases: A Literature Review of Basic Studies

Author:

Ho Tsung-Jung123,Chan Tzu-Min45,Ho Li-Ing6,Lai Ching-Yuan17,Lin Chia-Hsien8,Macdonald Iona9,Harn Horng-Jyh1011,Lin Jaung-Geng1,Lin Shinn-Zong4121314,Chen Yi-Hung9

Affiliation:

1. School of Chinese Medicine, China Medical University, Taichung, Taiwan

2. Division of Chinese Medicine, China Medical University Beigang Hospital, Yunlin County, Taiwan

3. Division of Chinese Medicine, Tainan Municipal An-Nan Hospital, China Medical University, Tainan, Taiwan

4. Center for Neuropsychiatry, China Medical University Hospital, Taichung, Taiwan

5. Everfront Biotech Inc., New Taipei City, Taiwan

6. Department of Respiratory Therapy, Taipei Veterans General Hospital, Taipei, Taiwan

7. Department of Emergency Medicine, China Medical University Hospital, Taichung, Taiwan

8. Department of Health Industry Management, Kainan University, Taoyuan, Taiwan

9. Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan

10. Department of Medicine, China Medical University, Taichung, Taiwan

11. Department of Pathology, China Medical University Hospital, Taichung, Taiwan

12. Department of Neurosurgery, China Medical University Beigan Hospital, Yunlin, Taiwan

13. Department of Neurosurgery, Tainan Municipal An-Nan Hospital, China Medical University, Tainan, Taiwan

14. Graduate Institute of Immunology, China Medical University, Taichung, Taiwan

Abstract

This review reports on recent findings concerning the effects of acupuncture and electroacupuncture (EA) on stem cell mobilization and differentiation, in particular with regard to neurogenesis. Traditional Chinese acupuncture has a history of over 2,500 years and is becoming more popular worldwide. Evidence has demonstrated that acupuncture may be of benefit in stroke rehabilitation, parkinsonism, dementia, and depression. This article reviews recent studies concerning the effects of acupuncture/EA on stem cell mobilization and on progenitor cell proliferation in the CNS. The reviewed evidence indicates that acupuncture/EA has beneficial effects in several neurodegenerative diseases, and it may prove to be a nondrug method for mobilizing stem cells in the CNS.

Publisher

SAGE Publications

Subject

Transplantation,Cell Biology,Biomedical Engineering

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