CD13: A Key Player in Multidrug Resistance in Cancer Chemotherapy-Reference-Cited by-同舟云学术

CD13: A Key Player in Multidrug Resistance in Cancer Chemotherapy

Published:2020-12-10 Issue:5 Volume:28 Page:533-540
ISSN:0965-0407
Container-title:Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
language:en
Short-container-title:oncol res

Author:

Guo Qie¹,Li Xiao¹,Cui Meng-Na¹,Sun Jia-Lin¹,Ji Hong-Yan¹,Ni Bei-Bei¹,Yan Mei-Xing²

Affiliation:

1. Department of Clinical Pharmacy, The Affiliated Hospital of Qingdao UniversityQingdao, ShandongP.R. China

2. Department of Pharmacy, Qingdao Women and Childrens HospitalQingdao, ShandongP.R. China

Abstract

Cancer is one of the most serious diseases that are harmful to human health. Systemic chemotherapy is an optimal therapeutic strategy for the treatment of cancer, but great difficulty has been encountered in its administration in the form of multidrug resistance (MDR). As an enzyme on the outer cell surface, CD13 is documented to be involved in the MDR development of tumor cells. In this review, we will focus on the role of CD13 in MDR generation based on the current evidence.

Publisher

Cognizant, LLC

Subject

Cancer Research,Oncology,General Medicine

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