1. *Laboratory of Molecular Clinical Chemistry, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan
2. §Department of Neurosciences, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0624
3. †Department of Plastic Surgery, School of Medicine, Kyoto University, Kyoto 606-8507, Japan