Prospects for Induced Pluripotent Stem Cell-Derived Hepatocytes in Cell Therapy-Reference-Cited by-同舟云学术

Prospects for Induced Pluripotent Stem Cell-Derived Hepatocytes in Cell Therapy

Published:2011-04 Issue:1 Volume:2 Page:1-8
ISSN:2155-1790
Container-title:Cell Medicine
language:en
Short-container-title:Cell Med

Author:

Iwamuro Masaya¹,Shahid Javed M.²,Yamamoto Kazuhide¹,Kobayashi Naoya²

Affiliation:

1. Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan

2. Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan

Abstract

Induced pluripotent stem (iPS) cells, first established in 2006, have the same characteristics of self-renew-ability and pluripotency as embryonic stem (ES) cells. iPS cells are inducible from patient-specific somatic cells; therefore, they hold significant advantages for overcoming immunological rejection as well as the ethical issues associated with the derivation of ES cells from embryos. Generation of patient-derived hepatocytes by iPS technology and their use in cell transplantation therapy for patients with liver disease is quite attractive. Here, we discuss recent advances and challenges in hepatocyte differentiation from iPS cells and their utility in cell therapy.

Publisher

SAGE Publications

Subject

Automotive Engineering

Link

http://journals.sagepub.com/doi/pdf/10.3727/215517911X575975

Reference95 articles.

1. Efficient Differentiation of Functional Hepatocytes from Human Embryonic Stem Cells

2. Isolated Hepatocyte Transplantation for Crigler-Najjar Syndrome Type 1

3. Expression of the liver-specific gene Cyp7a1 reveals hepatic differentiation in embryoid bodies derived from mouse embryonic stem cells

4. Hepatocyte differentiation of mesenchymal stem cells from human adipose tissue in vitro promotes hepatic integration in vivo

5. Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitro

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Dialysis based-culture medium conditioning improved the generation of human induced pluripotent stem cell derived-liver organoid in a high cell density;Scientific Reports;2022-12-01

2. One-step Passaging Technique for Induced Pluripotent Stem Cells, Suitable for Beginners in Stem Cell Research;Journal of Biomaterials and Tissue Engineering;2019-02-01

3. Small Molecules for Neural Stem Cell Induction;Stem Cells and Development;2018-03