A pseudohypoparathyroidism case with rarely seen intracranial calcification in childhood

Abstract

Introduction: Pseudohypoparathyroidism (PHPT) is characterized with end-organ resistance to parathormone (PTH) although normal hormone secretion and divided into two groups as Type 1 and Type 2. Furthermore, Type 1 PHPT is subdivided into 3 subgroups as ‘a’, ‘b’ and ‘c’. Case: Ten years old male case has admitted to our department with numbness and spasm in hands and we have detected hypocalcemia, hyperphosphatemia and increased parathormone levels. Cranial computed tomography revealed patchy calsific areas in phenotypically normal case. Conclusion: We primarily considered the case as having PHPT Type 1b or Type 2 and started active vitamine D and calcium replacement therapies which improved clinical and laboratory findings.