The Effects of Budesonide Nebulization on Post-operative Sore Throat After General Anaesthesia

Author:

Sneha S.ORCID,Nataraj Madagondapalli Srinivasan,Nagaraj Venkataramanareddy,Prasad Curopd Girivas

Abstract

Post-operative sore throat after general anaesthesia with endo-tracheal intubation occurs in 21% to 65% of patients.1 It has been reported to be one of the most undesirable outcomes in the post-operative period influencing patient satisfaction.2 Complaints range from minor throat irritation to debilitating pain, inability to swallow and temporary hoarseness of voice. Routine tracheal intubation for surgical procedures can result in pathological changes, trauma and nerve damage which may cause post operative sore throat. Several non-pharmacological methods like small sized endotracheal tubes,3 lubricating the endotracheal intubation tube with water soluble jelly, intubation after full relaxation, minimizing intra-cuff pressure and extubation when cuff is fully deflated, the pharmacological measures include gargling and nebulization with drugs like budesonide, beclomethasone, ketamine, lignocaine etc., have been studied.4,5 Budesonide is a non-halogenated glucocorticoid with powerful anti-inflammatory effects. It relieves congestion, reduces capillary permeability and oedema in the laryngeal mucosa. It is the only corticosteroid approved by FDA that can be used for aerosol inhalation.5 There are no studies on Indian population to evaluate the efficacy of budesonide on post-operative sore-throat. We found that Budesonide nebulization in a dose of 1 mg, 15 minutes before endotracheal intubation reduced the incidence and severity of sore-throat, cough and hoarseness of voice in the post-operative period up to 24 hrs in patients who underwent elective middle ear surgery under general anaesthesia. There were no systemic side effects with budesonide nebulization and patient satisfaction was good.

Publisher

Sri Lanka Journals Online

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3