IL-21 preferentially enhances IL-15-mediated homeostatic proliferation of human CD28+ CD8 memory T cells throughout the adult age span
Author:
Funder
NIA and National Cancer Institute
National Institutes of Health
Publisher
Wiley
Subject
Cell Biology,Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1189/jlb.0209086/fullpdf
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4. Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis;Effros;AIDS,1996
5. Loss of CD28 expression on CD8(+) T cells is induced by IL-2 receptor γ chain signaling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis;Borthwick;Int. Immunol.,2000
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