CD4+ T cell STAT3 phosphorylation precedes acute GVHD, and subsequent Th17 tissue invasion correlates with GVHD severity and therapeutic response-Reference-Cited by-同舟云学术

CD4+ T cell STAT3 phosphorylation precedes acute GVHD, and subsequent Th17 tissue invasion correlates with GVHD severity and therapeutic response

Published:2015-02-06 Issue:4 Volume:97 Page:807-819
ISSN:0741-5400
Container-title:Journal of Leukocyte Biology
language:en
Short-container-title:Journal of Leukocyte Biology

Author:

Betts Brian C.,Sagatys Elizabeth M.,Veerapathran Anandharaman,Lloyd Mark C.,Beato Francisca,Lawrence Harshani R.,Yue Binglin,Kim Jongphil,Sebti Said M.,Anasetti Claudio,Pidala Joseph

Funder

American Cancer Society

S. National Institutes of Health (NIH) National Heart, Lung, and Blood Institute

American Society for Blood and Marrow Transplantation/Bristol-Myers Squibb New Investigator

NIH National Cancer Institute

NIH National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Cell Biology,Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1189/jlb.5A1114-532RR/fullpdf

Reference44 articles.

1. Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen;Betts;Blood,2011

2. STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity;Betts;J. Leukoc. Biol.,2014

3. Dimer stability as a determinant of differential DNA binding activity of Stat3 isoforms;Park;J. Biol. Chem.,2000

4. STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease;Laurence;Immunity,2012

5. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation;Laurence;Immunity,2007

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5. T Helper Cell Lineage-Defining Transcription Factors: Potent Targets for Specific GVHD Therapy?;Frontiers in Immunology;2022-01-05