Affiliation:
1. Department of Optometry, Sharda University, Greater Noida, India
Abstract
Environmental variables have a considerable impact on the ocular surface, both structurally and functionally. The cornea, conjunctiva, and tear film form the ocular surface, which is essential for preserving visual clarity and comfort. UV radiation, air pollutants, allergens, and climatic changes can all upset the delicate balance of the ocular surface ecosystem, resulting in disorders such as dry eye disease (DED), allergic conjunctivitis, and photokeratitis. UV radiation is a well-documented environmental threat that can induce eye surface damage, both acute and chronic. Fine and ultrafine particles can get into the tear film and conjunctiva, producing oxidative stress and inflammation. Allergens such as pollen, dust mites, and pet dander cause allergic conjunctivitis, which is the most prevalent allergic eye illness. Climate variables such as temperature, humidity, and wind all have a substantial influence on ocular surface health. Understanding these environmental consequences necessitates a multidisciplinary strategy that combines ophthalmology, environmental science, and public health. Clinicians can measure the effect of environmental exposures on ocular health using diagnostic procedures such as tear film analysis, ocular surface imaging, and biomarker studies. Management options include preventative measures and therapies that are customized to individual illnesses. Preventive measures include wearing protective eyewear to shield against UV radiation and pollutants, using air purifiers to reduce indoor allergens, and avoiding outdoor activities during peak pollution hours. Emerging research focuses on elucidating molecular mechanisms underlying environmental-induced ocular surface disorders and developing novel therapies to mitigate their effects. By advancing knowledge in this field, we aim to enhance preventive strategies and therapeutic interventions, ultimately improving the quality of life for individuals affected by environmental-related ocular surface conditions.
Reference38 articles.
1. Thoft R. Role of the ocular surface in destructive corneal disease. Transactions of the Ophthalmological Societies of the United Kingdom. 1978; 98(3): 339-42.
2. Saxena R, Srivastava S, Trivedi D, Anand E, Joshi S, Gupta SK. Impact of environmental pollution on the eye. Acta Ophthalmologica Scandinavica. 2003; 81(5): 491-4. https://doi.org/10.1034/j.1600-0420.2003.00119.x
3. Zhou WP, Zhu YF, Zhang B, Qiu WY, Yao YF. The role of ultraviolet radiation in the pathogenesis of pterygia. Molecular medicine reports. 2016; 14(1): 3-15. https://doi.org/10.3892/mmr.2016.5223
4. WHO. WHO global report on trends in prevalence of tobacco use 2000–2025. WHO Tobacco Control Papers. 2019.
5. Collaborators G, Ärnlöv J. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet. 2020; 396(10258): 1223-49. https://doi.org/10.1016/S0140-6736(20)30752-2