Genomic landscape of intracranial meningiomas-Reference-Cited by-同舟云学术

Genomic landscape of intracranial meningiomas

Published:2016-09 Issue:3 Volume:125 Page:525-535
ISSN:0022-3085
Container-title:Journal of Neurosurgery
language:
Short-container-title:JNS

Author:

Bi Wenya Linda¹²,Abedalthagafi Malak³,Horowitz Peleg¹,Agarwalla Pankaj K.⁴²,Mei Yu¹,Aizer Ayal A.⁵,Brewster Ryan³,Dunn Gavin P.⁶,Al-Mefty Ossama¹,Alexander Brian M.⁵,Santagata Sandro³,Beroukhim Rameen²,Dunn Ian F.¹

Affiliation:

1. Department of Neurosurgery, Brigham and Women's Hospital;

2. Department of Cancer Biology, Dana-Farber Cancer Institute; and

3. Department of Pathology, Division of Neuropathology, Brigham and Women's Hospital,

4. Department of Neurosurgery, Massachusetts General Hospital;

5. Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and

6. Department of Neurosurgery, Pathology, and Immunology, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri

Abstract

Meningiomas are the most common primary intracranial neoplasms in adults. Current histopathological grading schemes do not consistently predict their natural history. Classic cytogenetic studies have disclosed a progressive course of chromosomal aberrations, especially in high-grade meningiomas. Furthermore, the recent application of unbiased next-generation sequencing approaches has implicated several novel genes whose mutations underlie a substantial percentage of meningiomas. These insights may serve to craft a molecular taxonomy for meningiomas and highlight putative therapeutic targets in a new era of rational biology-informed precision medicine.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

Genetics,Animal Science and Zoology

Link

https://thejns.org/downloadpdf/journals/j-neurosurg/125/3/article-p525.xml

Reference104 articles.

1. Loss of SUFU Function in Familial Multiple Meningioma

2. Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5

3. Malignant progression in meningioma: documentation of a series and analysis of cytogenetic findings

4. Radiation-induced meningiomas: clinical, pathological, cytokinetic, and cytogenetic characteristics

5. Schwannomatosis associated with multiple meningiomas due to a familial SMARCB1 mutation

Cited by 90 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Benign Adult Brain Tumors and Pediatric Brain Tumors;Neuroscience for Neurosurgeons;2024-01-25

2. Impact of molecular genetic profle of meningiomas on the clinical course and recurrence using combined modality treatment;Siberian journal of oncology;2024-01-03

3. Modelling Meningioma Using Organoids: A Review of Methodologies and Applications;Organoids;2023-12-04

4. NF2 mutation associated with accelerated time to recurrence for older patients with atypical meningiomas;British Journal of Neurosurgery;2023-04-25

5. Systematic Review of Meningiomas Revealed by Spontaneous Intracranial Hemorrhage: Clinicopathological Features, Outcomes, and Rebleeding Rate;World Neurosurgery;2023-04