Intracranial hemorrhage in patients with hemophilia

Abstract

✓ Intracranial hemorrhage occurred in four patients with hemophilia following mild head trauma. Three patients had severe factor VIII (antihemophilic factor, AHF) deficiency while one had mild (5.5%) AHF deficiency. The authors stress the need for immediate AHF replacement therapy and appropriate neurosurgical work-up, and a joint effort by hematologist and neurosurgeon to minimize neurological damage. In the four patients, three subdural hematomas, one epidural and one intracerebral hematoma were safely evacuated.