Suprasellar germinoma in association with Klinefelter's syndrome

Abstract

✓ A case is presented of suprasellar germinoma in a 20-year-old man with Klinefelter's syndrome. Hypogonadism is known to be a characteristic of Klinefelter's syndrome, and has often been described in cases of suprasellar germinoma. Thus, both pathological entities may mimic one another. It is emphasized that a chromosomal karyotype should be determined in every case of intracranial germ-cell tumor associated with hypogonadism.