Clinical and radiographic parameters associated with best versus worst clinical outcomes in minimally invasive spinal deformity surgery

Author:

Than Khoi D.1,Park Paul2,Fu Kai-Ming3,Nguyen Stacie4,Wang Michael Y.5,Chou Dean6,Nunley Pierce D.7,Anand Neel8,Fessler Richard G.9,Shaffrey Christopher I.10,Bess Shay11,Akbarnia Behrooz A.4,Deviren Vedat12,Uribe Juan S.13,La Marca Frank2,Kanter Adam S.14,Okonkwo David O.14,Mundis Gregory M.4,Mummaneni Praveen V.6,_ _

Affiliation:

1. Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon;

2. Department of Neurological Surgery, University of Michigan, Ann Arbor, Michigan;

3. Weill Cornell Brain and Spine Center, New York, New York;

4. San Diego Center for Spinal Disorders, La Jolla, California;

5. University of Miami Spine Institute, Miami, Florida;

6. Department of Neurological Surgery and

7. Spine Institute of Louisiana, Shreveport, Louisiana;

8. Orthopedic Spine Surgery, Cedars-Sinai, Los Angeles, California;

9. Department of Neurological Surgery, Rush University Medical Center, Chicago, Illinois;

10. Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia;

11. Rocky Mountain Scoliosis & Spine, Denver, Colorado;

12. Spine Center, UCSF Medical Center, San Francisco, California;

13. Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida; and

14. Department of Neurosurgery, University of Pittsburgh, Pennsylvania

Abstract

OBJECTIVE Minimally invasive surgery (MIS) techniques are increasingly used to treat adult spinal deformity. However, standard minimally invasive spinal deformity techniques have a more limited ability to restore sagittal balance and match the pelvic incidence–lumbar lordosis (PI-LL) than traditional open surgery. This study sought to compare “best” versus “worst” outcomes of MIS to identify variables that may predispose patients to postoperative success. METHODS A retrospective review of minimally invasive spinal deformity surgery cases was performed to identify parameters in the 20% of patients who had the greatest improvement in Oswestry Disability Index (ODI) scores versus those in the 20% of patients who had the least improvement in ODI scores at 2 years' follow-up. RESULTS One hundred four patients met the inclusion criteria, and the top 20% of patients in terms of ODI improvement at 2 years (best group, 22 patients) were compared with the bottom 20% (worst group, 21 patients). There were no statistically significant differences in age, body mass index, pre- and postoperative Cobb angles, pelvic tilt, pelvic incidence, levels fused, operating room time, and blood loss between the best and worst groups. However, the mean preoperative ODI score was significantly higher (worse disability) at baseline in the group that had the greatest improvement in ODI score (58.2 vs 39.7, p < 0.001). There was no difference in preoperative PI-LL mismatch (12.8° best vs 19.5° worst, p = 0.298). The best group had significantly less postoperative sagittal vertical axis (SVA; 3.4 vs 6.9 cm, p = 0.043) and postoperative PI-LL mismatch (10.4° vs 19.4°, p = 0.027) than the worst group. The best group also had better postoperative visual analog scale back and leg pain scores (p = 0.001 and p = 0.046, respectively). CONCLUSIONS The authors recommend that spinal deformity surgeons using MIS techniques focus on correcting a patient's PI-LL mismatch to within 10° and restoring SVA to < 5 cm. Restoration of these parameters seems to impact which patients will attain the greatest degree of improvement in ODI outcomes, while the spines of patients who do the worst are not appropriately corrected and may be fused into a fixed sagittal plane deformity.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

General Medicine

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