1. Ninewells Hospital and Medical School, University of Dundee;
2. Institute of Cardiovascular Sciences, Manchester Academic Health Sciences Centre, Salford;
3. Centre for Applied Pharmacokinetic Research, Manchester Pharmacy School;
4. Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool; and
5. University Hospital of North Midlands, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom
6. Centre for Biostatistics, Institution of Population Health, University of Manchester;
7. Faculty of Life Sciences, University of Manchester;