Combined pleomorphic xanthoastrocytoma-ganglioglioma with BRAF V600E mutation: case report-Reference-Cited by-同舟云学术

Combined pleomorphic xanthoastrocytoma-ganglioglioma with BRAF V600E mutation: case report

Published:2016-07 Issue:1 Volume:18 Page:53-57
ISSN:1933-0707
Container-title:Journal of Neurosurgery: Pediatrics
language:
Short-container-title:PED

Author:

Cicuendez Marta¹,Martinez-Saez Elena²,Martinez-Ricarte Francisco³,Asanza Esteban Cordero¹,Sahuquillo Juan³

Affiliation:

1. Department of Neurosurgery;

2. Department of Neuropathology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Spain

3. Department of Neurosurgery, Neurotraumatology, and Neurosurgery Research Unit; and

Abstract

Combined pleomorphic xanthoastrocytoma (PXA) and ganglioglioma (GG) is an extremely rare tumor, with fewer than 20 cases reported. The authors report a case of combined PXA-GG in an 18-year-old man with a history of seizures. The tumor showed necrosis and the BRAF V600E mutation on histological examination, with no evidence of tumor recurrence 1 year after gross-total resection. The BRAF V600E mutation was present, which suggests that both cell lineages may share a common cellular origin.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

General Medicine

Link

https://thejns.org/downloadpdf/journals/j-neurosurg-pediatr/18/1/article-p53.xml

Reference26 articles.

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