Defining future directions in spinal cord tumor research

Author:

Claus Elizabeth B.12,Abdel-Wahab May3,Burger Peter C.4,Engelhard Herbert H.5,Ellison David W.6,Gaiano Nicholas7,Gutmann David H.8,Heck Daniel A.9,Holland Eric C.10,Jallo George I.11,Kruchko Carol12,Kun Larry E.13,Maria Bernard L.14,Rumboldt Zoran15,Seminara Daniela16,Spinella Giovanna M.17,Stophel Linda18,Wechsler-Reya Robert19,Wrensch Margaret20,Gilbertson Richard J.21

Affiliation:

1. 1Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut;

2. 20Department of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts

3. 2Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami;

4. 3Departments of Pathology

5. 4Department of Neurosurgery, University of Illinois at Chicago;

6. 5Departments of Pathology

7. 6Neurology, and

8. 7Department of Neurology, Washington University School of Medicine, St. Louis, Missouri;

9. 8Malia's CORD Foundation, Covington, Kentucky;

10. 9Department of Neurosurgery, Memorial Sloan–Kettering Cancer Center, New York, New York;

11. 10Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland;

12. 11Central Brain Tumor Registry of the United States, (CBTRUS), Hinsdale, Illinois;

13. 12Radiological Sciences, and

14. 13Departments of Pediatrics and

15. 14Radiology, Medical University of South Carolina, Charleston, South Carolina;

16. 21National Cancer Institute, National Institutes of Health, Bethesda, Maryland;

17. 15Office of Rare Diseases Research and

18. 16Spinal Cord Tumor Association, Inc., Jay, Florida;

19. 17Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina;

20. 18Department of Neurosurgery, University of California, San Francisco, California; and

21. 19Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee;

Abstract

The relative rarity of spinal cord tumors has hampered the study of these uncommon nervous system malignancies. Consequently, the understanding of the fundamental biology and optimal treatment of spinal cord tumors is limited, and these cancers continue to inflict considerable morbidity and mortality in children and adults. As a first step to improving the outcome of patients affected with spinal cord tumors, the National Institutes of Health Office of Rare Diseases Research in cooperation with the National Cancer Institute and the National Institute of Neurological Disorders and Stroke convened a workshop to discuss the current status of research and clinical management of these tumors. The overall goal of this meeting was to initiate a process that would eventually translate fundamental basic science research into improved clinical care for this group of patients. Investigational priorities for each of these areas were established, and the opportunities for future multidisciplinary research collaborations were identified.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

General Medicine

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