Unusual primary secreting germ cell tumor of the spine

Author:

Massimino Maura1,Gandola Lorenza1,Spreafico Filippo1,Biassoni Veronica1,Terenziani Monica1,Pecori Emilia1,Arcella Antonietta1,Giangaspero Felice1

Affiliation:

1. Pediatric Oncology Unit, Radiotherapy Unit, Istituto Nazionale Tumori, Milan; Department of Experimental Medicine and Pathology, University of Rome “La Sapienza,” Rome; and INM Neuromed, Pozzilli, Isernia, Italy

Abstract

✓ The authors describe a young man with a rare primary spinal germ cell tumor that secreted β–human chorionic gonadotropin. The tumor was resected, and six courses of adjuvant chemotherapy consisting of cisplatin, bleomycin and etoposide were administered together with irradiation to the craniospinal area. An additional dose of radiation was delivered to the tumor site after the first four chemotherapy sessions. The patient was well without any neurological deficit or iatrogenic sequela 33 months after diagnosis. The occurrence of this rare tumor located primarily in the spine warrants attention in pathological studies of spinal tumors in young patients.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

General Medicine

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