Use of artificial neural networks to predict surgical satisfaction in patients with lumbar spinal canal stenosis

Author:

Azimi Parisa1,Benzel Edward C.2,Shahzadi Sohrab1,Azhari Shirzad1,Mohammadi Hasan Reza1

Affiliation:

1. 1Department of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran; and

2. 2Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio

Abstract

Object The purpose of this study was to develop an artificial neural network (ANN) model for predicting 2-year surgical satisfaction, and to compare the new model with traditional predictive tools in patients with lumbar spinal canal stenosis. Methods The 2 prediction models included an ANN and a logistic regression (LR) model. The patient age, sex, duration of symptoms, walking distance, visual analog scale scores of leg pain or numbness, the Japanese Orthopaedic Association score, the Neurogenic Claudication Outcome Score, and the stenosis ratio values were determined as the input variables for the ANN and LR models that were developed. Patient surgical satisfaction was recorded using a standardized measure. The ANNs were fed patient data to predict 2-year surgical satisfaction based on several input variables. Sensitivity analysis was applied to the ANN model to identify the important variables. The receiver operating characteristic–area under curve (ROC-AUC), Hosmer-Lemeshow statistics, and accuracy rate were calculated for evaluating the 2 models. Results A total of 168 patients (59 male, 109 female; mean age 59.8 ± 11.6 years) were divided into training (n = 84), testing (n = 42), and validation (n = 42) data sets. Postsurgical satisfaction was 88.7% at 2-year follow-up. The stenosis ratio was the important variable selected by the ANN. The ANN model displayed a better accuracy rate in 96.9% of patients, a better Hosmer-Lemeshow statistic in 42.4% of patients, and a better ROC-AUC in 80% of patients, compared with the LR model. Conclusions The findings show that an ANN can predict 2-year surgical satisfaction for use in clinical application and is more accurate compared with an LR model.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

General Medicine

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