Glomus tumor and glomangioma of the nerve

Author:

Scheithauer Bernd W.1,Rodriguez Fausto J.1,Spinner Robert J.2,Dyck P. James3,Salem Ayman4,Edelman Fredric L.4,Amrami Kimberly K.5,Fu Yao-Shi6

Affiliation:

1. Departments of Laboratory Medicine and Pathology

2. Neurosurgery

3. Neurology, and

4. Departments of Neurosurgery and

5. Radiology, Mayo Clinic, Rochester, Minnesota; and

6. Pathology, Providence Saint Joseph Medical Center, Burbank, California

Abstract

✓ As a rule, normal human nerve does not contain glomus bodies. Nonetheless, rare examples of glomus tumors do arise in peripheral nerves of various sizes. Their pathobiological characteristics are poorly understood, but reported examples have been small and clinically benign. The authors identified in 1 patient each a glomus tumor and a glomangioma involving nerve. Clinical histories as well as imaging and surgical findings were reviewed. All available H & E–stained slides were examined in both cases. Immunohistochemical stains and electron microscopy, as appropriate, were also performed. The lesions were subtotally and completely resected, respectively. An uneventful postoperative recovery was noted in both patients. Glomus tumors and glomangiomas can involve major nerves on rare occasions. They seem to follow a favorable clinical course, and conservative resection can be of benefit.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

Genetics,Animal Science and Zoology

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