Outcomes of endoscopic treatment for early correction of craniosynostosis in children: a 26-year single-center experience

Author:

Domínguez Leonardo12,Rivas-Palacios Claudio123,Barbosa Mario M.4,Escobar Maria Andrea56,Puello Florez Elvira17,García-Ballestas Ezequiel138

Affiliation:

1. Department of Pediatric Neurosurgery, Napoleón Franco Pareja Children’s Hospital (Child’s House), Cartagena, Colombia;

2. Department of Neurosurgery, University of Cartagena, Colombia;

3. Center of Biomedical Research (CIB), Faculty of Medicine, University of Cartagena, Colombia;

4. Trauma and Emergency Epidemiology Research Group, University of Valle, Cali, Colombia;

5. Faculty of Medicine, Rafael Nuñez University, Cartagena, Colombia;

6. Department of Arts and Humanities, International University of Valencia, Spain;

7. Faculty of Medicine, University El Sinu, Cartagena, Colombia; and

8. Latinamerican Council of Neurocritical Care (CLaNI), Bogota, Colombia

Abstract

OBJECTIVE Surgery is the cornerstone of craniosynostosis treatment. In this study, two widely accepted techniques are described: endoscope-assisted surgery (EAS) and open surgery (OS). The authors compared the perioperative and reconstructive outcomes of EAS and OS in children ≤ 6 months of age treated at the Napoleón Franco Pareja Children’s Hospital (Cartagena, Colombia). METHODS According to the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement, patients with defined criteria who underwent surgery to correct craniosynostosis between June 1996 and June 2022 were retrospectively enrolled. Demographic data, perioperative outcomes, and follow-up were obtained from their medical records. Student t-tests were used for significance. Cronbach’s α was used to assess agreement between estimated blood loss (EBL). Spearman’s correlation coefficient and the coefficient of determination were used to establish associations between the results of interest, and the odds ratio was used to calculate the risk ratio of blood product transfusion. RESULTS A total of 74 patients met the inclusion criteria; 24 (32.4%) belonged to the OS group and 50 (67.6%) to the EAS group. There was a high interobserver agreement quantifying the EBL. The EBL, transfusion of blood products, surgical time, and hospital stay were shorter in the EAS group. Surgical time was positively correlated with EBL. There were no differences between the two groups in the percentage of cranial index correction at 12 months of follow-up. CONCLUSIONS Surgical correction of craniosynostosis in children aged ≤ 6 months by EAS was associated with a significant decrease in EBL, transfusion requirements, surgical time, and hospital stay compared with OS. The results of cranial deformity correction in patients with scaphocephaly and acrocephaly were equivalent in both study groups.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

General Medicine

Reference50 articles.

1. Diagnosis and management of suture-related concerns of the infant skull;Hersh DS,2021

2. Update in management of craniosynostosis;Xue AS,2022

3. Neurosurgery;Wilkins RH,1996

4. Endoscopic craniectomy for early surgical correction of sagittal craniosynostosis;Jimenez DF,1998

5. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies;von Elm E,2007

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