Diffuse leptomeningeal involvement by a ganglioglioma in a child

Author:

Wacker Margaret R.,Cogen Philip H.,Etzell Joan E.,Daneshvar Laleh,Davis Richard L.,Prados Michael D.

Abstract

✓ Gangliogliomas are tumors composed of neuronal and glial elements that typically grow slowly by expansion only. This report describes a 20-month-old girl with a ganglioglioma that extensively involved the subarachnoid space; microscopic foci of tumor were found in the brain and spinal cord. Despite chemotherapy and radiation therapy, the child died 5 months after diagnosis. Molecular genetic analysis showed loss of chromosome 17p DNA sequences in the tumor tissue.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

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2. Early Onset Epilepsy Caused by Low-Grade Epilepsy-Associated Tumors and Focal Meningeal Involvement;Brain Sciences;2020-10-18

3. Primary diffuse leptomeningeal oligodendrogliomatosis with an isolated 1p deletion;British Journal of Neurosurgery;2019-11-21

4. Impact of surgery, adjuvant treatment, and other prognostic factors in the management of anaplastic ganglioglioma;Child's Nervous System;2018-03-29

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