Adjuvant hypofractionated partial-brain radiation therapy for pediatric Ewing sarcoma brain metastases: case report-Reference-Cited by-同舟云学术

Adjuvant hypofractionated partial-brain radiation therapy for pediatric Ewing sarcoma brain metastases: case report

Published:2016-04 Issue:4 Volume:17 Page:434-438
ISSN:1933-0707
Container-title:Journal of Neurosurgery: Pediatrics
language:
Short-container-title:PED

Author:

van Dams Ritchell¹,Park Henry S.¹,Alomari Ahmed K.²,Ricciardi Adele S.³,Rao Harini⁴,McNamara Joseph⁴,DiLuna Michael L.³⁴,Bindra Ranjit S.¹²

Affiliation:

1. Departments of Therapeutic Radiology,

2. Pathology,

3. Neurosurgery, Section of Pediatric Neurosurgery, and

4. Pediatrics, Section of Pediatric Hematology and Oncology, Yale School of Medicine, New Haven, Connecticut

Abstract

This case report demonstrates that hypofractionated partial-brain radiation therapy with limited margins is a reasonable approach following gross tumor resection of Ewing sarcoma metastases to the brain. The patient presented with 2 intracranial metastases treated with gross-total resection followed by radiation therapy to 30 Gy in 5 fractions. The patient experienced symptomatic treatment-related inflammatory changes with resolution after receiving dexamethasone. He remains alive at 21 months of follow-up with no evidence of disease.

Publisher

Journal of Neurosurgery Publishing Group (JNSPG)

Subject

General Medicine

Link

https://thejns.org/downloadpdf/journals/j-neurosurg-pediatr/17/4/article-p434.xml

Reference18 articles.

1. Fractionated stereotactic radiotherapy to the post-operative cavity for radioresistant and radiosensitive brain metastases

2. Hypofractionated Stereotactic Radiotherapy in Five Daily Fractions for Post-Operative Surgical Cavities in Brain Metastases Patients with and without Prior Whole Brain Radiation

3. Clinical outcome of hypofractionated conventional conformation radiotherapy for patients with single and no more than three metastatic brain tumors, with noninvasive fixation of the skull without whole brain irradiation

4. CNS involvement in Ewing's sarcoma

5. Hypofractionated radiosurgery for intact or resected brain metastases: defining the optimal dose and fractionation

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2. CyberKnife Stereotactic Radiosurgery for an Unusual Case of Large Brain Metastases From Ewing's Sarcoma in a Pediatric Patient;Advances in Radiation Oncology;2022-07

3. Radical radiotherapy for paediatric solid tumour metastases: An overview of current European protocols and outcomes of a SIOPE multicenter survey;European Journal of Cancer;2021-03

4. Pediatric Brain Metastases;Radiation Oncology for Pediatric CNS Tumors;2017-10-31