Clinical outcomes with intravascular ultrasound guidance of percutaneous coronary interventions: a targeted literature review of randomized controlled trials

Abstract

The use of intravascular ultrasound (IVUS) to guide and optimize percutaneous coronary intervention (PCI) has been subject to robust clinical investigation for the last three decades. In this narrative review, we summarize the major clinical outcomes of the randomized controlled trials evaluating the potential benefit of IVUS-guided PCI, compared with either angiography alone or other coronary imaging and physiology technologies. These studies, spanning decades and continents, provide the most rigorous evidence base that clinicians can use to guide real-world decision making regarding the utility of IVUS guidance during PCI in contemporary clinical practice.