Abstract
Testicular cancer is often overshadowed by other cancers despite being the most common cancer in men aged 15 to 34 years. This systematic review focuses on the potential of machine learning and deep learning techniques in the areas of testicular cancer imaging and histopathology, where artificial intelligence (AI) could assist in diagnosis, evaluation, and prognostication. Various studies have highlighted AI’s ability to accurately distinguish between benign and malignant lesions and characterisation within malignant lesions using magnetic resonance imaging (MRI) radiomics. Models have also been used in predicting histopathological findings to allow for greater accuracy and reproducibility. Further work is required to explore AI implementation in ultrasound imaging, which is the cheapest and most used modality.