Managing Spasticity in People With Multiple Sclerosis: A Goal-Oriented Approach to Intrathecal Baclofen Therapy

Author:

Jarrett Louise1,Leary Siobhan M.2,Porter Bernadette3,Richardson Davina4,Rosso Tiziana5,Powell Michael6,Thompson Alan J.7

Affiliation:

1. Louise Jarrett is a Spasticity Management Clinical Nurse Specialist, National Hospital for Neurology and Neurosurgery, University College London Hospitals, Queen Square, London, United Kingdom.

2. Siobhan M. Leary is a Research Fellow, Institute of Neurology, Queen Square, London, United Kingdom.

3. Bernadette Porter is a Multiple Sclerosis Clinical Nurse Specialist, National Hospital for Neurology and Neurosurgery, University College London Hospitals, Queen Square, London, United Kingdom.

4. Davina Richardson is a Clinical Physiotherapy Specialist, National Hospital for Neurology and Neurosurgery, University College London Hospitals, Queen Square, London, United Kingdom.

5. Tiziana Rosso was a Visiting Research Fellow, Institute of Neurology, Queen Square, London, United Kingdom, at the time this paper was prepared. Dr. Rosso is now at Servizio di Neurologia ad indirizzo Riabilitativo, Dipartimento di Scienze Neurologiche e della Visione, Universita' degli Studi di Verona, Italy.

6. Michael Powell is a Consultant Neurosurgeon, National Hospital for Neurology and Neurosurgery, University College London Hospitals, Queen Square, London, United Kingdom.

7. Alan J. Thompson is a Professor of Clinical Neurology and Neurorehabilitation, Institute of Neurology, Queen Square, London, United Kingdom.

Abstract

ABSTRACT The effectiveness of intrathecal baclofen therapy (ITB) in the management of severe spasticity in people with multiple sclerosis (MS) was reviewed retrospectively. The multidisciplinary team reviewed the medical, therapy, and nursing notes of 19 people with MS who were treated with ITB. The audited information included surgical procedures, postoperative complications, medical side effects, dose requirements, and multidisciplinary input. Seventeen people were included in the audit. A total of 23 problems and 34 functional goals as objects for ITB treatment were recorded. Eighty-seven percent of the patients had sustained improvement in at least one problem, and 79% in at least one goal. Only two patients had no sustained improvement in any problem or goal. These results suggest that ITB can be an effective intervention in people with severe spasticity in MS. However, this approach requires careful patient selection, a dynamic goal-oriented approach, expert implantation, and ongoing evaluation of individual responses to treatment over time. (Int J MS Care. 2001; 3(4): 10–21)

Publisher

Consortium of Multiple Sclerosis Centers

Subject

Advanced and Specialised Nursing,Clinical Neurology

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1. Spasticity;Reference Module in Neuroscience and Biobehavioral Psychology;2024

2. Intrathecal Agents Used for Spasticity;Neuraxial Therapeutics;2023

3. Neuromodulation in multiple sclerosis;Multiple Sclerosis Journal;2017-11

4. Being and becoming a spasticity nurse specialist: a reflexive narrative study;British Journal of Neuroscience Nursing;2015-06-02

5. Goals and outcomes for non ambulant children receiving continuous infusion of intrathecal baclofen;European Journal of Paediatric Neurology;2012-09

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