Artifacts in Amine Analysis from Anodic Oxidation of Organic Solvents upon Electrospray Ionization for Mass Spectrometry-Reference-Cited by-同舟云学术

Artifacts in Amine Analysis from Anodic Oxidation of Organic Solvents upon Electrospray Ionization for Mass Spectrometry

Published:2012-06 Issue:3 Volume:18 Page:301-312
ISSN:1469-0667
Container-title:European Journal of Mass Spectrometry
language:en
Short-container-title:Eur J Mass Spectrom (Chichester)

Author:

Abburi Ramarao¹,Kalkhof Stefan²,Oehme Ramona¹,Kiontke Andreas¹,Birkemeyer Claudia¹

Affiliation:

1. Institute of Analytical Chemistry, University of Leipzig, Linnéstr. 3, 04103 Leipzig, Germany

2. Department of Proteomics, Helmholtz-Centre for Environmental Research—UFZ, Permoserstr. 15, 04318 Leipzig, Germany

Abstract

Different phenylenediamines were used to explore anodic oxidation in solution during electrospray ionization (ESI) mass spectrometry analysis. In our experiments, a series of unknown ionic species was detected in the phenylenediamine solutions. Our results propose that reactions of phenylenediamines with species formed by anodic oxidation of typical ESI solvents during the electrospray ionization process such as formaldehyde are producing these peaks. Identification of these compounds inter alia suggests formal alkylation, a reaction not reported so far as a result of electrolytic oxidation in the prospective organic solvents.

Publisher

SAGE Publications

Subject

Spectroscopy,Atomic and Molecular Physics, and Optics,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1255/ejms.1187

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