Mass Spectrometry as a Tool for the Determination of Heats of Tautomerization of Thioamides in the Gas Phase-Reference-Cited by-同舟云学术

Mass Spectrometry as a Tool for the Determination of Heats of Tautomerization of Thioamides in the Gas Phase

Published:2005-02 Issue:1 Volume:11 Page:53-63
ISSN:1469-0667
Container-title:European Journal of Mass Spectrometry
language:en
Short-container-title:Eur J Mass Spectrom (Chichester)

Author:

Allegretti P.E.¹,Milazzo C.B.¹,Furlong J.J.P.¹

Affiliation:

1. LADECOR (UNLP), División Química Orgánica, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Calle 47 & 115, (1900) La Plata, Argentina

Abstract

Tautomerism of several thioamides was studied by mass spectrometry. The analysis of the corresponding mass spectra allowed some fragmentations to be assigned to specific tautomers and heats of tautomerization to be determined through temperature effects and electron energy studies. Experimental determinations were strongly supported by theoretical calculations. AM1 semi-empirical results indicate that the thioamide–thioimidol equilibrium can be studied by mass spectrometry. Also, additional evidence was obtained regarding tautomerism occurrence between neutral species.

Publisher

SAGE Publications

Subject

Spectroscopy,Atomic and Molecular Physics, and Optics,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1255/ejms.691

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