Gas-Phase Intramolecular Elimination Reaction Studies of Steviol Glycosides in Positive Electrospray and Tandem Mass Spectrometry-Reference-Cited by-同舟云学术

Gas-Phase Intramolecular Elimination Reaction Studies of Steviol Glycosides in Positive Electrospray and Tandem Mass Spectrometry

Published:2009-02 Issue:1 Volume:15 Page:11-21
ISSN:1469-0667
Container-title:European Journal of Mass Spectrometry
language:en
Short-container-title:Eur J Mass Spectrom (Chichester)

Author:

Upreti Mani¹,Clos John F.¹,Somayajula Kasi V.¹,Milanowski Dennis J.²,Mocek Ulla²,DuBois Grant E.¹,Prakash Indra¹

Affiliation:

1. The Coca-Cola Company, PO Box 1734, Atlanta, GA 30301, USA

2. AMRI, Bothell Research Center, 18804 North Creek Parkway, Bothell, WA 98011, USA

Abstract

This paper reports the first study of the gas-phase intramolecular elimination reaction of steviol glycosides in positive electrospray mass spectrometry. The observed glycosylated product ions are proposed to be formed via an intramolecular elimination of sugar units from the parent molecule ion. It was further proven by MS/MS studies and deuterium labeling experiments with one of the steviol glycosides, rebaudioside A. These mass spectrometric results confirmed that the new glycosylated product ions observed are most likely formed by the combination of glucose moieties (Glu) II–IV and Glu I via a gas-phase intramolecular elimination reaction.

Publisher

SAGE Publications

Subject

Spectroscopy,Atomic and Molecular Physics, and Optics,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1255/ejms.981

Reference27 articles.

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