Determination of Copper Level and Affecting Factors in Maternal Blood

Abstract

While copper (Cu), which is found as a trace element in the body, is included in the structure of many enzymes, it can have negative effects on the pregnant and fetus due to its amount changing depending on various factors during pregnancy. Prematurity, nutritional and absorption disorders, overnutrition, chronic diarrhea are seen in Cu deficiency, while copper toxicity has been suggested to cause liver and kidney necrosis and gastrointestinal bleeding. Sociodemographic results were obtained by applying both blood analysis and questionnaire with random sampling method to pregnant women who came to Karabük Training and Research Hospital (n = 50) to give birth. The average age of pregnant women is 29.2 ± 5.39, 80% of them do not work, 20% of them are primary school graduates and 26% are secondary school graduates. In addition, it was determined that 18% of pregnant women had chronic disease, 12% had gestational diabetes mellitus and 4% had hypertension. In our study, the mean Cu level in maternal blood was found to be 200.7 ± 43.3 μg / dl. In addition, while there was no correlation between maternal age, life expectancy, proximity to the factory, bus station and main road and copper level of the pregnant women (p> 0.05), a significant relationship was found between the blood copper levels in the spouses of high school and secondary school graduates (p