Türkiye'nin Hatay İlinde Orak Hücre Hastalığı Olan Hastalarda COVİD-19'un Klinik Sonuçları

Abstract

Objective:The covid-19 infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) can be mortal particularly due to respiratory system involvement and coagulopathy.On the other hand, respiratory system involvement and coagulopathy are among the major causes of mortality in sickle cell patients as well.There are conflicting results in the literature on the mortality rates caused by covid-19 infection in sickle cell patients.For this reason, we aimed to show the course of covid-19 infection in sickle cell patients. Method:Our study was created from the data of 21 sickle cell patients in the adult age group who were infected with covid-19.The laboratory and imaging results of these patients were reviewed. Result:İt was found that these patients had increased mortality rates compared to the normal population.It was concluded that mainly the medical histories of the patients were effective on the associated mortality rates, yet it was also observed that certain laboratory parameters (C-reactive Protein, Ferritin, D-Dimer and Lactate Dehydrogenase) were elevated in mortal patients. Conclusion:İt is recommended that the transfusion treatments be started early in patients with a poor clinical and laboratory prognosis due to the high mortality rate in this patient group, in addition to the treatments administered in relation to covid-19 infection.