Aksiyal spondiloartritli hastalarda D vitamini eksikliğinin yorgunluk ve depresyon üzerine etkisi

Abstract

Aim: In this study, we aimed to examine the effect of vitamin D deficiency on fatigue and depression in patients with axial spondyloarthritis (Ax-SpA). Methods: This cross-sectional study included 141 Ax-SpA patients. Demographic information of the patients was recorded. The Hospital Anxiety and Depression Scale, Visual Analog Scale, Fatigue Severity Scale, and Ankylosing Spondylitis Disease Activity Score were used to evaluate depression, anxiety, pain, fatigue, and disease activity levels, respectively. Vitamin D levels were classified as deficiency (20 ng/ml). Results: A total of 141 patients enrolled in the study (67 female and 74 male). Vitamin D levels were deficient in 14.2%, insufficient in 56%, and sufficient in 29.8% of cases. In the evaluation of fatigue, 20.6% of the cases were evaluated as normal, 60.3% as tired, and 19.1% as chronically tired. Although fatigue was detected in 79.4% of Ax-SpA patients, fatigue scores were not associated with vitamin D deficiency (p=0.191). There were no significant differences between the vitamin D groups (deficiency, insufficiency, and normal) in fatigue and depression scores, sex, disease duration, and activity. Conclusion: Vitamin D deficiency is not associated with fatigue, depression, or disease activity in patients with Ax-Spa. Regardless of vitamin D deficiency, patients with depression and fatigue should be evaluated and managed appropriately, and the management of vitamin D deficiency should not be ignored.