This book studies the cohomology of locally symmetric spaces for GL(N) where the cohomology groups are with coefficients in a local system attached to a finite-dimensional algebraic representation of GL(N). The image of the global cohomology in the cohomology of the Borel–Serre boundary is called Eisenstein cohomology, since at a transcendental level the cohomology classes may be described in terms of Eisenstein series and induced representations. However, because the groups are sheaf-theoretically defined, one can control their rationality and even integrality properties. A celebrated theorem by Langlands describes the constant term of an Eisenstein series in terms of automorphic L-functions. A cohomological interpretation of this theorem in terms of maps in Eisenstein cohomology allows the authors to study the rationality properties of the special values of Rankin–Selberg L-functions for GL(n) × GL(m), where n + m = N. The book carries through the entire program with an eye toward generalizations. The book should be of interest to advanced graduate students and researchers interested in number theory, automorphic forms, representation theory, and the cohomology of arithmetic groups.