Prevention of Neurotoxicity by High-dose Folinic Acid Rescue after High-dose Methotrexate and Intrathecal Methotrexate without Compromising Cure inspite of Previous Transient Leukoencephalopathy after Intrathecal Methotrexate-Reference-Cited by-同舟云学术

Prevention of Neurotoxicity by High-dose Folinic Acid Rescue after High-dose Methotrexate and Intrathecal Methotrexate without Compromising Cure inspite of Previous Transient Leukoencephalopathy after Intrathecal Methotrexate

Published:2009-08-15 Issue:8 Volume:38 Page:743-744
ISSN:0304-4602
Container-title:Annals of the Academy of Medicine, Singapore
language:en
Short-container-title:Ann Acad Med Singap

Author:

Hamidah Alias¹,Lope Raja Juanita Raja¹,Latiff Zarina Abdul¹

Affiliation:

1. National University of Malaysia, Kuala Lumpur, Malaysia

Publisher

Academy of Medicine, Singapore

Subject

General Medicine

Reference6 articles.

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2. Mahoney DH, Shuster JJ, Nitscke R, Lauer SJ, Steuber CP, Winick N, et al. Acute neurotoxicity in children with B-precursor acute lymphoblastic leukemia: an association with intermediate-dose intravenous methotrexate and intrathecal triple therapy: a Pediatric Oncology Group study. J Clin Oncol 1998;16:1712-22.

3. Dunkelman H, Earl HM, Twelves C. Acute reversible neurological deficit following intrathecal chemotherapy. Cancer Chemother Pharmacol 1991;27:329-30.

4. Cohen IJ, Stark B, Kaplinsky C, Weitz R, Matz S, Lerman P, et al. Methotrexate-induced leucoencephalopathy is treatable with high-dose folinic acid: A case report and analysis of the literature. Pediatr Hematol Oncol 1990;7:79-87.

5. Cohen IJ. Defining the appropriate dosage of folinic acid after high-dose methotrexate for childhood acute lymphatic leukemia that will prevent neurotoxicity without rescuing malignant cells in the central nervous system. J Pediatr Hematol Oncol. 2004;26:156-63.