Isolated remote site musculoskeletal Mycobacterium bovis infections after BCG immunisation in immunocompetent children

Author:

Fong Jiawen1,Chia Dawn Sinn Yii1,Chew Darryl Ee Ming2,Wong Kenneth Pak Leung2

Affiliation:

1. Department of Hand & Reconstructive Microsurgery, Sengkang General Hospital, Singapore

2. Department of Orthopaedic Surgery, KK Women’s and Children’s Hospital, Singapore

Abstract

The Bacillus Calmette–Guerin (BCG) vaccine, derived from wild-type Mycobacterium bovis, is administered in an attenuated form to prevent Mycobacterium tuberculous (MTB) infections in children residing in endemic regions. Since the introduction of the Singapore Tuberculosis Elimination Programme in 1997—specifying mandatory BCG-immunisation at birth—the incidence fell drastically to 32.6 per 100,000 population in 2021,1 with the paediatric population contributing 2.1% of infections.2

Publisher

Academy of Medicine, Singapore

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