Affiliation:
1. Brookhaven National Library, NY, USA
Abstract
This paper provides a brief review of the radiochemistry of radiopharmaceuticals used in positron emission tomography (PET). It includes some history of PET, the basic formation of radionuclides in a cyclotron target, the processing of the precursor molecules into a useful PET radiotracer and the clinical significance and outlook for PET radiotracers. This review is based on a series of recent books and articles outlining the fundamental goals of PET and how radiochemistry plays a part in achieving these goals. It is also drawn from the literature that has been developed in PET over the last 30 years since PET became a research and valuable clinical tool. PET is a growing field and the clinical applications of the chemistry and technology have just begun to be explored. There is a great deal left to do in order to explore the full potential of PET in the clinic.
Publisher
Academy of Medicine, Singapore
Reference60 articles.
1. Brownell GL, Sweet WH. Localization of brain tumors with positron emitters. Nucleonics 1953;11:40-5.
2. Brownell GL, Burnham CA. MGH positron camera. In: Freedman GS, editor. Tomographic Imaging in Nuclear Medicine. New York: The Society of Nuclear Medicine, 1973:154-64.
3. Kuhl DE, Edwards RQ. Image separation radioisotope scanning. Radiology 1963;80:653-61.
4. Kuhl DE, Edwards RQ. Reorganizing data from transverse section scans of the brain using digital processing. Radiology 1968; 91:975-83.
5. Robertson JS, Marr RB, Rosenblum M, Radeka V, Yamamoto YL. 32- crystal positron transverse section detector. In: Freedman GS, Editor. Tomographic Imaging in Nuclear Medicine. New York: The Society of Nuclear Medicine, 1973:142-53.
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献