Perinatal outcomes of pregnancies affected by COVID-19 in Singapore: A cohort study

Author:

Lim Alicia May1,Low Jia Ming1,Tan Mary Grace2,Ngeow Alvin Jia Hao2,Tong Wing Yee3,Chua Ka Hee4,Yung Chee Fu4,Ho Selina Kah Ying2,Amin Zubair1,Yeo Kee Thai3

Affiliation:

1. National University Hospital, Singapore

2. Singapore General Hospital, Singapore

3. KK Women’s and Children’s Hospital, Singapore

4. Duke-NUS Medical School, Singapore

Abstract

Pregnant women and infants were not spared from the coronavirus disease 2019 (COVID-19) after it was first identified in December 2019.1,2 In the beginning of the pandemic, a lack of data on transmission risks and outcomes of pregnancies affected by SARS-CoV-2, impacted perinatal clinical decision-making.1,3 We report the perinatal outcomes of pregnancies affected by COVID-19 in Singapore, covering the period from initial virus identification to the emergence of the Omicron variant in late 2021. We investigated the impact of COVID-19 vaccination and the Omicron variant on the perinatal outcomes of infected pregnant women and their newborns.

Publisher

Academy of Medicine, Singapore

Subject

General Medicine

Reference7 articles.

1. Yeo KT, Oei JL, De Luca D, et al. Review of guidelines and recommendations from 17 countries highlights the challenges that clinicians face caring for neonates born to mothers with COVID-19. Acta Paediatr 2020;109:2192-207.

2. Choi H, Lee EJ, Ahn YS, et al. Effects of the Omicron variant on perinatal outcomes in full-term neonates. BMC Pediatr 2022;22:625.

3. Mattar CN, Kalimuddin S, Sadarangani SP, et al. Pregnancy Outcomes in COVID-19: A Prospective Cohort Study in Singapore. Ann Acad Med Singap 2020;49:857-69.

4. World Health Organization. Overview of COVID-19 in pregnancy, January 2022. https://cdn.who.int/media/docs/default-source/ health-care-readiness---post-covid-19-condition/1_overview-ofcovid-19-in-pregnancy_michelle-giles.pdf?sfvrsn=55d43f45_5. Accessed 31 March 2023.

5. Government of Singapore. White Paper on Singapore’s Response to COVID-19, March 2023. https://www.gov.sg/article/ covid-19-white-paper. Accessed 31 March 2023.

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