BACKGROUND
Oral mucosal lesions manifest as a first sign of immune mediated disorders. Lichen planus, pemphigus &pemphigoid are the most frequent immunologically mediated mucocutaneous diseases with oral involvement
OBJECTIVE
A dental surgeon is the first person to come across these lesions that have similar clinical characteristics, therefore their identification based solely on oral lesions is a challenging issue for dentists, leading to a delay in the establishment of a correct diagnosis and suitable management of the patient.
METHODS
Clinical information was retrieved from records and histopathologic features were reviewed from archives dated 1997 – 2018. ( n = 6300 ).
RESULTS
Out of 6300 specimens, these immunologically mediated diseases accounted for 105 (1.66%) cases, of which 86 (1.36%) were lichen planus, 4 (0.06%) were pemphigus and 15 (0.23%) were pemphigoid.
CONCLUSIONS
From the results of this study, it can be inferred that immune-mediated diseases with oral manifestations are comparatively scarce among oral lesions. The present study comprises the retrospective assessment of oral immunologically mediated diseases, in which data regarding the 3 diseases were extracted and analyzed altogether